Abortion MTP Pills – Mifepristone and Misoprostol
A safe and effective method to end early pregnancy with the help of two medicines- Mifepristone and Misoprostol is termed medication or medical abortion. The drugs are taken alone or in combination, administered orally, buccally, sublingually, or vaginally to cause expulsion of conception contents from the womb. A Pregnancy Termination with Abortion pills is non-surgical and performed in the first ten weeks of fetus age. Pregnancy over 12 weeks must be ended with surgery.
Mifepristone is anti-progesterone medicine that ends early pregnancy and is taken at the start of medical abortion. It is FDA certified in aiding several health uses, including pregnancy termination. The mifepristone tablets are safe and function to thin the uterus’s endometrial lining and dilate the cervix.
Misoprostol is a synthetic prostaglandin E1 potent inhibitor of human gastric acid secretion. It also causes the cervix to soften and the uterus to contract. Prostaglandin E1 causes myometrial contractions by interacting with specific receptors on myometrial cells. This interaction changes calcium concentration, thereby initiating muscle contraction and expulsion of the fetal egg.
Killpreg kit Use
Combipack of Mifepristone Misoprostol is used for medical termination of a developing intra-uterine pregnancy with a gestational age up to 77 days as measured from the first day of the Last Menstrual Period (LMP) in a presumed 28-day cycle.
Mifepristone: This medication produces vaginal bleeding and uterine cramps to regulate menstruation (MR). Nausea, vomiting, and diarrhea were often reported as adverse effects: pelvic discomfort, fainting, headache, and dizziness. Asthenia occurred infrequently.
Tablets of Misoprostol may cause diarrhea, abdominal pain, nausea, flatulence, dyspepsia, headache, vomiting, and constipation, as well as shivering, hyperthermia, dizziness, pain from uterine contractions, severe vaginal bleeding, shock, pelvic pain, and uterine rupture (requiring surgical repair, hysterectomy, and/or salpingo-oophorectomy).
The combination of Mifepristone and Misoprostol should not be given to anyone else. A licensed physician must supervise the administration. While the combination of Mifepristone and Misoprostol was recommended for the patient’s unique situation, it may not be appropriate for another patient. It may be harmful to other women if she is or becomes pregnant.
Before initiating therapy with Mifepristone, any intrauterine device (IUD) should be removed. Menstrual Regulation (MR) surgery is advised in situations when the combination of Mifepristone and Misoprostol does not work.
At their previous visit, patients who were pregnant have an increased risk of fetal deformity due to the therapy. To manage Menstrual Regulation (MR)/pregnancy failures, surgical termination/MVA (Manual Vaccum Aspiration) is recommended.
Although specific medication or dietary interactions with Mifepristone have not been examined, based on the medicine’s metabolism through CYP 3A4, ketoconazole, itraconazole, erythromycin, and grapefruit juice may all decrease the drug’s metabolism (increasing serum, levels of Mifepristone).
Misoprostol has not been found to impair aspirin’s beneficial effects on the signs and symptoms of rheumatoid arthritis. When used at therapeutic doses, Misoprostol has no clinically significant effect on aspirin’s absorption, blood levels, or antiplatelet effects.
Use During Pregnancy & Breastfeeding
Mifepristone & Misoprostol is licensed for use in the termination of pregnancy (up to 63 days gestation) and has no other recognized usage during pregnancy.
Mifepristone is not known to be excreted in human milk. However, many hormones with a similar molecular structure are excreted in breast milk.
Due to the uncertain effects of Mifepristone on newborns, women who are breastfeeding should visit their health care practitioner to determine if they should discard their breast milk for a few days after drug delivery.
Store in a cool (below 30 deg; C) and dry place, protected from light and moisture. Keep out of the reach of the children.