Can I Take Misoprostol And Mifepristone Together? -

January 06, 2023 10:04

April 11, 2023 11:36

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Can I Take Misoprostol And Mifepristone Together?

According to a recent study, women can inject the two components of the so-called “abortion pill” concurrently, preferably 24 hours apart. A second study revealed that the medication is safe for late-trimester medical abortions.

By preventing the hormone progesterone from being produced, Mifepristone, often known as RU486, stops pregnancy. When the medication is taken by itself, substances related to conception may stay in the uterus and increase the risk of infection. This is why health professionals also advise Misoprostol, which makes the uterus contract and securely expels the pregnancy tissue. Misoprostol can be purchased online.

In April, both studies are released.

According to the first study, administering the Mifepristone and Misoprostol kit simultaneously is at least as effective for ending a pregnancy as doing so 24 hours earlier. One of the medical professionals added, “It really comes down to comfort for the mom. There was a time when women seeking medications for abortion had to undergo a process that took several days. It gives women flexibility as well. Things don’t mean they have to do it this way, but it opens up a window of opportunity.”

In this procedure, 1,128 women received oral Mifepristone before being randomly assigned to either receive Misoprostol vaginally shortly after at the doctor’s office or 24 hours later at home. The rate of total abortions was the same in both groups and was unaffected by a woman’s stage of pregnancy.

The second trial examined 323 pregnant women between 63 and 84 days. They came from different cities. 24 to 48 hours after taking the Mifepristone, the ladies used Misoprostol vaginally. Misoprostol was administered orally or intravaginally, don’t two more times as necessary. Eighty-nine percent of women who attempted to end their pregnancies were successful. Most women (64,8%) and the very majority (26,8%) of women expressed satisfaction with the experience. Nearly all respondents (94%) said they would definitely recommend medical abortion to a friend, and 90.04 percent indicated they would use it themselves if no more procedures were needed in the future.

Of the 1.3 million medical abortions carried out annually, 55% occur before nine weeks of gestation. Another 34% of medical abortions occur between 10 and 12 weeks of gestation. Although not always available and carrying significant health risks, surgical abortion is also influential during this time. According to the expert, the second study demonstrates that a medicinal abortion is a very safe and powerful substitute for surgical abortion. A medical expert stated that “medical abortion has been employed frequently for early phase gestation but not so usually for the later part of the trimester.” It is now firmly established through additional study that this is a viable and practical choice for women.


Mifepristone or RU486 ends the pregnancy by blocking the production of the progesterone hormone. When the drug is used alone, materials connected to conceiving can remain in the uterus, causing the risk of infection. This is why medical experts also prescribe Misoprostol, which causes the uterus to contract and safely expel the pregnancy tissue. Both the studies were published in April. And a second study found out that the drug is secure for late first-trimester medical abortions.

For this sequence, 1,128 women were administered Mifepristone orally and were then randomly selected to either take Misoprostol vaginally soon at the doctor’s clinic or 24 hours later at home. Medical abortion is a very safe and effective alternative to surgical abortion, a medical expert says. 55% of the 1.3 million medical abortions performed each year happen before nine weeks of gestation. Surgical abortion during this period is also effective but not always accessible.